Cytochrome b5 isoform d

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August undefined, 2024

WebThe housefly cytochrome b5 is a 134 amino acid protein ( Guzov et al., 1996) with 48% sequence identity with the orthologous rat cytochrome b5. Its N-terminal domain of … WebCytochrome b5 type B Imported Gene names Name CYB5B Imported Organism names Organism Homo sapiens (Human) Imported Taxonomic identifier 9606 NCBI Taxonomic lineage Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Primates > Haplorrhini > Catarrhini > …

Cytochrome B5 - an overview ScienceDirect Topics

WebThis isoform is inducible by ethanol and isoniazid and is responsible in part for the metabolism of acetaminophen. 50 The product of acetaminophen's cytochrome P450 metabolism is a highly... WebNADPH Cytochrome P450 oxidoreductase (CPR) is commonly regarded as the electron carrier for the P450-catalyzed reactions in monolignol biosynthesis. Here we show that cytochrome b5 isoform D (CB5D) is an indispensable electron shuttle intermediate specific for S-lignin biosynthesis. Arabidopsis CB5D localizes on endoplasmic reticulum … ph scorpion\\u0027s

The roles of cytochrome b5 in cytochrome P450 reactions

WebProtein sequence alignment of A. thaliana cytochrome b5 isoform B (accession number: At2g32720) with rat cytochrome b5 (accession number: NP_071581.1). The proteins … WebSep 1, 2024 · Cytochrome b5 (CB5) is a small heme-binding protein, known as an electron donor delivering reducing power to the terminal enzymes involved in oxidative reactions. WebNov 4, 2024 · The .gov means it's official. Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're on a federal government site. ph scale without colour

AT1G26340(CB5-A) - Arabidopsis

Webcytochrome B5 isoform D GeneRIFs: Gene References Into Functions Over-expression of AtCb5-D conferred reduced ethylene sensitivity similar to that conferred by … WebThe gene for NADH-cytochrome b 5 reductase is located on chromosome 22. At least 18 different NADH-cytochrome b 5 reductase mutations, mostly missense, have been described in three types of enzyme deficiency (171,172). The diagnosis of NADH-cytochrome b 5 reductase deficiency is made by direct assay of the enzyme. how do you abbreviate freewayWebJan 11, 2001 · Cytochrome b5 isoform E 1 publication. Short names. AtCb5-E 1 publication. Alternative names. Cytochrome b5 isoform 1; Cytochrome b5 isoform A 1 publication (AtCb5-A 1 publication) Gene names. Name. CYTB5-E. Synonyms. B5-A, CB5-A 1 publication, CB5-E 1 publication. ORF names. MNC6.10. Ordered locus names. ph schock

"WebCytochrome b5 reductase is a flavoprotein that is produced as two different isoforms that have different localizations. The amphipathic microsomal isoform, found in all cell types with the exception of erythrocytes, consists of one hydrophobic membrane-anchoring domain and a larger hydrophilic flavin catalytic domain. " - Cytochrome b5 isoform d

Cytochrome b5 isoform d

Biochemical Investigation of Membrane-Bound Cytochrome b5 …

WebJun 12, 2024 · Here, we show that cytochrome b 5 isoform D (CB5D) is an indispensable electron shuttle protein specific for S-lignin biosynthesis. Arabidopsis ( Arabidopsis thaliana ) CB5D localizes to the endoplasmic reticulum membrane and physically … WebDec 1, 2024 · Each structure depicts the purported membrane-bound isoform except for CYB5R4, which exists only as a soluble protein. ... CYB5R4 is the only CYB5R family …

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WebJul 12, 2013 · Furthermore, the mitochondrial isoform of CYB5 (CYB5B) is clearly identified as an essential component of the mARC-containing N-reductase system in human cells. The participation of the microsomal isoform (CYB5A) in N-reduction could be excluded by siRNA-mediated down-regulation in HEK-293 cells and knock-out in mice.

WebCytochrome b 5 influenced the C17-20 lyase reaction but had little impact on the 17alpha-hydroxylase activity of the cytochrome P450. In this system, apo-cytochrome b5 was as … WebMar 29, 2024 · CYB5; MCB5; METAG Summary The protein encoded by this gene is a membrane-bound cytochrome that reduces ferric hemoglobin (methemoglobin) to ferrous hemoglobin, which is required for stearyl-CoA-desaturase activity. Defects in this gene are a cause of type IV hereditary methemoglobinemia.

WebCytochrome b5 deficiency; Specialty: Endocrinology: Cytochrome b 5 deficiency is a rare condition and form of isolated 17,20-lyase deficiency caused by deficiency in … WebDec 4, 2013 · The AtCb5–D isoform, which consists of 140 residues, localizes to the ER membrane (Maggio et al., 2007). The AtCb5–D clone that was isolated from the screen encodes the last 38 residues of the protein, consisting of the transmembrane domain preceded by 11 cytosolic residues and followed by an 11-residue luminal tail (Figure 1a).

WebCytochrome B5 isoform D Gene CYTB5-D Status UniProtKB reviewed (Swiss-Prot) Organism Arabidopsis thaliana (Mouse-ear cress) Amino acids 140 Protein existence Evidence at protein level Annotation score 4/5 Entry Feature viewer Publications External links History Function

WebMar 1, 2001 · Cytochrome b5 isoform D 1 publication ( AtCb5-D 1 publication ) Gene names Name CB5-A 1 publication Synonyms CB5-D 1 publication ORF names … ph scorpion\u0027sWebProtein sequence alignment of A. thaliana cytochrome b5 isoform B (accession number: At2g32720) with rat cytochrome b5 (accession number: NP_071581.1). The proteins share 48% sequence identity and 73% sequence similarity. Identical residues are highlighted with dark blue color. Sequences were aligned using the ClustalW algorithm and analyzed with ph scale youtubeWebAug 19, 2024 · Cytochrome b5 (CB5) is a small heme-binding protein, known as an electron donor delivering reducing power to the terminal enzymes involved in oxidative reactions. In plants, the CB5 protein family … how do you abbreviate franceWebApr 27, 2024 · Here, we show that cytochrome b5 isoform D (CB5D) is an indispensable electron shuttle protein specific for S-lignin biosynthesis. Arabidopsis (Arabidopsis thaliana) CB5D localizes to the ... ph scratchpad\u0027sWebAug 1, 2010 · We demonstrated recently that cytochrome b 5 plays an important in vivo role in hepatic cytochrome P450 (P450) function [ J Biol Chem 283: 31385–31393, 2008]. We have now generated a model in which cytochrome b 5 has been deleted in all tissues [cytochrome b 5 c omplete n ull (BCN)], which surprisingly results in a viable mouse … ph scratchpad\\u0027sWebAug 30, 2013 · Cytochrome b5 reductase transfers electrons from NADH to cytochrome b5 proteins, which then transfer the electrons to fatty acid desaturases (Shanklin and Cahoon, 1998), hydroxylases (Nagano et al., 2009), and other enzymes. ... While the function of this isoform is unknown, ... how do you abbreviate ft and inchesWebApr 27, 2024 · Here, we overexpressed the full-length membrane-bound cytochrome b5 isoform B from the model plant Arabidopsis thalianain Escherichia coli, purified the protein employing detergents as well as styrene–maleic acid (SMA) copolymers, and biochemically characterized the protein. how do you abbreviate gallons